Kaiser Permanente Mid-Atlantic HCV repository (KPMAS)
KPMAS is an integrated healthcare system that serves more than 500,000 individuals in in the Northeast and includes publicly and privately insured individuals. The KPMAS HCV repository includes information on demographics, clinical encounters, laboratory test results, and pharmacy data for enrollees.
Rodriguez CV, Rubenstein KB, Linas B, Hu H, Horberg M. Increasing hepatitis C screening in a large integrated health system: science and policy in concert. Am J Manag Care. 2018;24(5):e134-e140. PMID: 28733097
Boston Alcohol Research Collaboration on HIV/AIDS (Boston ARCH) Cohort
The Boston ARCH is a cohort of HIV-infected patients with risky alcohol or drug use. The cohort uses a traditional observational design, with every 6-month study visits conducted outside of the clinical setting. Study assessments capture detailed characterization of alcohol and drug use, including validated measures of quantity and frequency of use of a variety of substances, as well as their impact on quality of life, criminal activity, and general health status.
Health Insurance Claims
Marketscan – Truven Health Analytics
MarketScan® databases capture health insurance claims-based data from more than 200 million unique patients dating back to 2006. The Commercial claims database captures complete payment information, including patient out-of-pocket co-payments and deductibles as well as clinical diagnoses and procedures associated with each claim. Specialty pharmacy and mail order pharmacy data are included.
Barocas JA, Wang J, White LF, Tasillo A, Salomon JA, Freedberg KA, Linas BP. Hepatitis C Testing Increased Among Baby Boomers Following The 2012 Change To CDC Testing Recommendations. Health Affairs. 2017 Dec;36(12):2142-2150. PMID: 29200354
Morgan JR, Schackman BR, Leff JA, Linas BP, Walley AY. Injectable naltrexone, oral naltrexone, and buprenorphine utilization and discontinuation among individuals treated for opioid use disorder in a United States commercially insured population. J Subst Abuse Treat. 2018;85:90-96. PMID: 28733097
Health Care Cost Institute (HCCI)
The Health Care Cost Institute (HCCI) database contains detailed claims data for approximately 50 million individuals per year (2008-2016) insured with Aetna, Humana, UnitedHealthcare, and Kaiser Permanente in all 50 states and the District of Columbia, covering about 30% of all privately insured populations nation-wide. The HCCI data compliment MarketScan because MarketScan tends to include largely employer-based health plans, whereas HCCI includes many self-insured individuals and Medicare Advantage plans. The data include claims for all covered services including inpatient, outpatient, physician services, and pharmacy claims.
The Symphony Health “Integrated Dataverse” contains nationally-representative, detailed, and comprehensive prescription claims data from over 80% of US retail pharmacies that account for approximately 90% of prescriptions filled in the country. Symphony Health data include sales to institutions, including private and government hospitals, clinics, home healthcare providers, HMO captive pharmacies, mail-order pharmacies, and prisons. Data come directly from payers and processors of prescription drug claims, and contain information on consumer out-of-pocket costs, as well as demographic and socioeconomic factors such as age, gender, race, education, income, insurance type, and the prescriber’s 5-digit zip code. All payers are captured by the data, including private, Medicare fee-for-service, managed Medicare, Medicaid, and self-pay.
Murphy SM, Morgan JR, Jeng PJ, Schackman BR. Will converting naloxone to over‐the‐counter status increase pharmacy sales? Health Services Research. 2019.