Research Highlight

Publications funded by or feature contributions from CHERISH.

March 4, 2025 Research Highlight

Hepatitis C Virus Screening in Pregnant and Nonpregnant Women After Universal Screening Guidelines

Hepatitis C virus (HCV) testing guidelines were updated in 2020 to provide universal, one-time screening for adults ages 18 through 79 and during each pregnancy. This departure from their 2013 recommendation not only aims to improve early detection of HCV across age groups but also acknowledges pregnancy as a critical period for diagnosing and treating […]

January 17, 2025 Research Highlight

Research Highlights Prevention Efforts in Fentanyl Overdoses

The overwhelming majority of those in New York City who obtained a naloxone kit to counteract opioid overdose had a high need for the drug, according to a new study by Weill Cornell Medicine investigators and the New York City Department of Health and Mental Hygiene. The study, published Jan. 16 in the Journal of Urban Health, […]

December 31, 2024 Research Highlight

Offering Buprenorphine in Homeless Shelters in Massachusetts Projects Life- and Cost-saving Results

Overdose is the leading cause of death among people with opioid use disorder (OUD) who are experiencing homelessness. Innovative care models that meet this population outside of office-based settings can improve access to buprenorphine, a medication for treating OUD, and avert fatal overdoses. In this study, Avik Chatterjee, lead author and addiction specialist at Boston […]

Rebecca Arden Harris, Tara Calderbank, and Yuhua Bao.
December 18, 2024 Research Highlight

We’re barely using a key resource to help people with addiction

Rachel was making her 25th visit to the emergency department. The wound on her leg from injecting drugs had spread to her entire calf and required a lengthy course of antibiotic treatment in the hospital. The few times she had been admitted to the hospital, she had left without finishing treatment because the pain and […]

December 3, 2024 Research Highlight

Cost-Effectiveness of Fibrosis Staging

More than 4 million people in the U.S. live with a hepatitis C virus (HCV) diagnosis. However, as of 2022, fewer than one-third of individuals infected with HCV have been cured due to barriers related to high direct-acting antiviral (DAA) pricing and the steps involved in determining someone’s degree of liver disease or fibrosis. In […]

November 25, 2024 Research Highlight

A Cost-Effectiveness of Implementation Facilitation to Promote Emergency Department–Initiated Buprenorphine for Opioid Use Disorder

In the last eight years, emergency departments (EDs) have seen an influx of visits related to opioid use disorder (OUD). For the same reason, researchers have been citing EDs to be a critical setting and reachable moment for initiating OUD medications, the gold standard of care. Buprenorphine is advantageous as a low-barrier OUD treatment compared […]

November 6, 2024 Research Highlight

Racial and Ethnic Disparities Along the Hepatitis C Care Cascade Among Priority Populations

Over the last two decades, injection opioid use has increased among reproductive-aged women, with resultant increases in mother-to-child hepatitis C virus (HCV) transmissions in the U.S. Direct-acting antiviral (DAA) treatment is highly effective at reducing and eliminating the risk of HCV transmissions. Yet, studies show lower odds of receiving DAA treatment for women compared to […]

October 14, 2024 Research Highlight

Economic Costs and Outcomes that Matter to Patients

One of the key questions researchers ask when conducting an economic evaluation is: How much does this intervention cost to an individual, organization, or society at large? The process requires researchers to identify the perspectives of affected stakeholders and analyze the costs related to the intervention. To better understand the burdens and economic impact of […]

October 14, 2024 Research Highlight

Improving Care for Opioid Use Disorder in the Criminal-Legal System

Substance use disorders (SUD), and especially opioid use disorder (OUD), are prevalent within the criminal-legal system.  Recently, there has been increased alignment of OUD care across the criminal-legal system with the patient-centered American Society of Addiction Medicine guidelines. Whether by choice or through legislation, carceral facilities are increasingly offering FDA-approved medications for OUD (MOUD), which […]

September 12, 2024 Research Highlight

Insurance Instability for Patients with Opioid Use Disorder in the Year After Diagnosis

Access to health insurance is crucial to gaining the necessary diagnostic and therapeutic services to achieve and maintain good health. Insurance is especially necessary to access medications for opioid use disorder (MOUD) as the cost of MOUD can be a barrier to staying in treatment. If insurance coverage is disrupted, MOUD treatment may be more […]

August 12, 2024 Research Highlight

Association between claims-based setting of diagnosis and treatment initiation among Medicare patients with Hepatitis C

Direct-acting antivirals (DAAs) have been available since 2015 for hepatitis C (HCV). Nonetheless, very few patients with HCV initiate DAA treatment, ranging from 5% to 30%. The location where a patient is first diagnosed can also influence the care patients receive afterward, especially when a referral to a specialist or coordinated care is needed. In […]

July 10, 2024 Research Highlight

Medicaid-Covered Peer Support Services Used by Enrollees With Opioid Use Disorder

Peer support services (PSS) play an increasingly important role in supporting recovery for people with substance use disorder (SUD). Through these services, peer support workers combine lived experience and professional training to provide health education, encouragement and empathy, recovery modeling, and concrete assistance in overcoming barriers to recovery. As of 2018, 37 Medicaid programs covered PSS for SUD. In a research letter in JAMA Network Open, Dr. Yuhua Bao, professor of population health sciences, and colleagues investigated multi-state utilization of Medicaid-covered PSS in 2019. Researchers found that overall use of Medicaid-covered […]

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