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April 5, 2023 Collaboration

Penn LDI & CHERISH Launch New Online Communications Training Course for Academic Researchers

The University of Pennsylvania’s Leonard Davis Institute of Health Economics (LDI), which since 2019 has been offering the [email protected] in-person communications course to help academic researchers translate and disseminate their findings more widely, has developed and just launched a free, online course providing an introduction to the same topics. The new training resource is a […]

February 2, 2022 Collaboration

Advancing Evidence-Based Substance Use Disorder Treatment Policies

If you want to reform state laws to require detox facilities to include medications like buprenorphine and methadone in their treatments, you should start by changing the “hearts and minds” of those who oppose it, Rebekah Gee, MD, MPH, MHSPR, told the January 14, 2022 Penn LDI/CHERISH Virtual Conference at the University of Pennsylvania. Keynoting a gathering organized […]

August 12, 2021 Research Highlights

Patient Preferences Do Not Explain Racial Disparities in Opioid Prescribing

Why are Black patients less likely than white patients to be prescribed opioids for acute pain in the emergency department (ED)? While many theories have been put forward (ranging from racial differences in patients’ pain management preferences to providers’ false beliefs in biological differences between racial groups), the specific mechanisms underpinning these disparities are unclear. […]

June 16, 2021 Research Highlights

Prescription Drug Monitoring Program Mandates Affect Use of Opioids to Treat Acute, Severe Pain

Prescription drug monitoring programs (PDMP) have been crucial tools to address unsafe opioid prescribing. High rates of prescribing stoked the flames of the opioid crisis in the early 2000s, but opioid prescriptions have steadily decreased over the past decade. Unfortunately, opioid-related deaths have continued to rise each year. Many states have enacted comprehensive mandates that all clinicians consult the PDMP […]

December 14, 2020 Research Highlights

More X-Waivered Obstetrician-Gynecologists Needed to Address Opioid Epidemic

Going Beyond a 2% Solution “X-the X Waiver” has been the slogan used by physicians and public health advocates fighting for greater access to buprenorphine, a medication proven to treat opioid use disorder (OUD) with higher effectiveness than many other treatments. Despite being safe, however, buprenorphine is tightly regulated, and to prescribe it, health care providers […]

November 9, 2020 Research Highlights

Dissemination Science to Advance the Use of Simulation Modeling

COVID-19 has brought simulation modeling to the foreground of public discourse, as policy makers and stakeholders project the effects of different interventions to “flatten the curve.” Simulation models allow investigators to tinker with different conditions of the world to observe how they affect future outcomes; however, translating the models’ results to the public can be […]

July 17, 2020 Collaboration

CHERISH Awarded Five-year Center of Excellence Grant to Continue Substance Use Health Economics Research

The National Institute on Drug Abuse (NIDA) of the National Institutes of Health has awarded the Center for Health Economics of Treatment Interventions for Substance Use, HCV and HIV (CHERISH) a five-year grant to continue the Center’s activities as a national center of excellence. CHERISH was founded in 2015 as a multi-institutional center for health […]

May 6, 2020 Research Highlights

Simulation Modeling Presents Opportunities To Support The Public Health Response To The Opioid Crisis In North America

Although there are several evidence-based cost-effective interventions for people with opioid use disorder (OUD), they are underutilized. Questions remain regarding intervention selection, and cost of service delivery. Simulation modeling offers an opportunity to support decision making to address the syndemic of opioid overdose, HIV, and hepatitis C (HCV). In an article recently published in the International Journal […]

July 10, 2019 Research Highlights

No Safe Dose for That First Opioid Prescription

LDI Senior Fellows Zack Meisel, Benjamin Sun, and colleagues have a striking and sobering chart in a recent Annals of Emergency Medicine article on initial opioid prescriptions in the emergency department. They tracked how many “opioid-naïve” patients (i.e., those without a record of opioid use in the previous year) had persistent or high-risk opioid prescription use in the subsequent […]

March 15, 2019 Research Highlights

Starting Opioid Use Disorder Treatment in the Emergency Department: Physician-reported barriers and facilitators

Every day, we hear about the staggering toll of the opioid overdose crisis. This is particularly salient in Philadelphia, which has one of the highest overdose death rates among major U.S. cities. Despite effective medications for opioid use disorder, such as buprenorphine and methadone, few people receive treatment. The ongoing challenge is to expand access to these lifesaving treatments […]

March 7, 2019 Research Highlights

Strengthening Partnerships Between Substance Use Researchers and Policy Makers

Comprehensive evidence-based policy is crucial in combatting the substance use crisis. CHERISH Investigators from the University of Pennsylvania Leonard Davis Institute Zachary Meisel, Julia Mitchell, Daniel Polsky and Janet Weiner published a new study in Substance Abuse Treatment Prevention and Policy that describes how eighteen policy makers involved in the delivery of health services engage with substance […]

February 5, 2018 Research Highlights

Penn LDI Research Brief: Association between Electronic Medical Record Implementation of Default Opioid Prescription Quantities and Prescribing Behavior in Two Emergency Departments

M. Kit Delgado, Frances S. Shofer, Mitesh S. Patel, Scott Halpern, Christopher Edwards, Zachary F. Meisel, Jeanmarie Perrone Journal of General Internal Medicine – first online January 16, 2018 KEY FINDINGS Setting a low quantity of opioid tablets as the default option in electronic medical record prescribing orders may “nudge” clinicians to prescribe fewer opioids. When […]

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